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Cellular Receptor Sensitivity Tuning

Meaning

Cellular Receptor Sensitivity Tuning is the clinical practice of optimizing the responsiveness of cellular receptors to their corresponding hormones or signaling molecules. Over time, chronic high hormone exposure or inflammatory states can lead to receptor downregulation or desensitization, diminishing the biological effect of circulating hormones. This tuning process aims to restore the intrinsic ability of cells to effectively “hear” hormonal messages, maximizing the impact of endogenous or administered compounds. It is a critical factor in maintaining robust endocrine function.