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Cellular Receptor Fidelity

Meaning

Cellular Receptor Fidelity refers to the precise and reliable capacity of a cell’s hormone receptors to accurately bind to their specific signaling molecules and transmit the correct biological message into the cell. High fidelity ensures that the endocrine system’s messages are clearly received and translated into the appropriate physiological response, such as glucose uptake or protein synthesis. Loss of this crucial fidelity, often due to chronic overexposure or receptor degradation, is a fundamental mechanism underlying hormone resistance and aging.