The specialized branch of neuroscience that investigates the structure, function, and physiological processes of individual neurons and glial cells, focusing on their electrical and chemical signaling properties. This field is crucial for understanding how neuroendocrine signals are received, processed, and transmitted throughout the central and peripheral nervous systems. It provides the microscopic foundation for comprehending complex brain functions, including hormonal regulation and cognitive processes.
Origin
Cellular neuroscience emerged as a distinct discipline with the advent of advanced electrophysiological and molecular techniques that allowed for the detailed study of single cells. Its connection to endocrinology is profound, as hormones act as primary modulators of neuronal excitability, synaptogenesis, and neurogenesis. The field underpins our understanding of how hormonal fluctuations impact mental health and cognitive vitality.
Mechanism
At the cellular level, communication relies on action potentials and synaptic transmission mediated by neurotransmitters and neuropeptides. Hormones, being lipid-soluble or acting via cell-surface receptors, modulate these mechanisms by altering ion channel function, regulating neurotransmitter release, or changing gene expression within the neuron. For example, steroid hormones can cross the cell membrane to bind intracellular receptors, directly influencing the neuronal proteome and thus its long-term function and survival.
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