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Cellular Memory

Meaning

Cellular memory is the phenomenon where individual cells retain a record of past environmental exposures or stimuli through stable, long-lasting changes in their molecular and epigenetic programming. This ‘memory’ dictates how a cell will respond to future challenges, influencing processes like immune function, metabolic efficiency, and cellular senescence. It represents the inherited regulatory state that is passed down through cell divisions, not through the DNA sequence itself. Understanding this memory is key to addressing chronic metabolic dysfunction.