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Cellular Insulin Sensitivity

Meaning

Cellular insulin sensitivity describes the degree to which a cell’s receptors and downstream signaling cascades respond effectively to the presence of insulin. This metric is crucial for maintaining glucose homeostasis, as high sensitivity allows cells to efficiently uptake glucose from the bloodstream following a meal. Optimal cellular sensitivity is a hallmark of metabolic health and is vital for energy regulation and tissue function. Diminished sensitivity, or insulin resistance, is a core pathology in metabolic syndrome and Type 2 Diabetes Mellitus.