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Cellular Inbox Capacity

Meaning

A conceptual term describing the finite ability of a target cell to effectively receive, process, and transduce multiple simultaneous hormonal and metabolic signals. When the cellular environment is overwhelmed by high concentrations of hormones or inflammatory signals, the “inbox” becomes congested, leading to impaired receptor function and reduced signaling efficiency. This capacity is a critical determinant of cellular responsiveness and overall metabolic sensitivity. Maintaining adequate capacity is essential for preventing signal resistance and maintaining hormonal communication integrity.