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Cellular Environment Signaling

Meaning

Cellular environment signaling describes the complex communication network between a cell and its immediate surroundings, involving the exchange of biochemical and biophysical cues that dictate cellular behavior. This signaling includes paracrine and autocrine factor release, extracellular matrix interactions, and the sensing of nutrient availability or mechanical stress. The integrity of this signaling is paramount, as it governs fundamental processes such as cell survival, proliferation, differentiation, and the coordinated function of tissues. Dysregulation in this environment is a key driver of aging and disease pathology.