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Cellular Entropy

Meaning

Cellular Entropy, within the framework of biological aging, refers to the progressive and irreversible loss of ordered structure and functional organization within individual cells over the passage of time, inevitably leading toward senescence and systemic dysfunction. This phenomenon is the cellular manifestation of the second law of thermodynamics, representing the gradual accumulation of molecular damage, misfolded proteins, and increasingly inefficient organelle function. This systemic disorganization at the cellular level is a fundamental and unavoidable driver of the overall aging phenotype.