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Cellular Cross-Talk

Meaning

Cellular Cross-Talk refers to the complex, continuous, and bidirectional communication and interaction that occurs between different cell types within a tissue, organ, or entire system. This signaling involves the dynamic exchange of chemical messengers, including hormones, cytokines, growth factors, and micro-vesicles, enabling highly coordinated tissue function and systemic homeostatic maintenance. Cellular cross-talk is essential for fundamental biological processes like tissue repair, immune surveillance, and endocrine feedback regulation. Dysregulation of this intricate communication network is frequently implicated in chronic disease states and the overall aging process.