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Cellular Communication Anti-Aging

Meaning

Therapeutic or lifestyle strategies focused on restoring the efficiency and fidelity of signaling pathways between cells that typically decline with age. As we age, cells accumulate damage and enter senescence, leading to a state where they inappropriately signal to surrounding tissues, creating a pro-inflammatory microenvironment known as the Senescence-Associated Secretory Phenotype (SASP). Effective anti-aging intervention requires the optimization of these critical intercellular conversations to maintain tissue function and hormonal responsiveness. The disruption of this communication is a hallmark of systemic aging.