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Cellular Chaperone Systems

Meaning

Cellular Chaperone Systems represent the sophisticated intracellular network of proteins dedicated to preserving proteostasis, the vital balance of protein folding, trafficking, and degradation within every cell. These systems are crucial for ensuring newly synthesized polypeptides rapidly achieve their correct functional three-dimensional structure. Their proper function prevents the accumulation of misfolded or damaged proteins, a key factor in cellular stress and aging. In the hormonal context, these chaperones are essential for the integrity and responsiveness of hormone receptors and downstream signaling molecules.