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Cellular Architecture Refinement

Meaning

Cellular architecture refinement is the dynamic biological process by which the precise structural organization of individual cells, particularly neurons, is sculpted and maintained throughout development and adulthood. This refinement involves the continuous remodeling of dendritic spines, the pruning of unnecessary synaptic connections, and the reorganization of the extracellular matrix surrounding the cells. It is a critical component of neuroplasticity, ensuring that neural circuits remain efficient, adaptable, and capable of encoding new information and memories. Disruption of this refinement process can lead to compromised cognitive function and neurological pathology.