Question 1

What is the Meaning of CCTA?

Accepted Answer

CCTA, which stands for Coronary Computed Tomography Angiography, is a non-invasive diagnostic imaging procedure that utilizes computed tomography technology and an intravenous contrast agent to visualize the coronary arteries. This procedure is specifically used to assess the presence, extent, and characteristics of atherosclerotic plaque and stenosis within the vascular network supplying the heart muscle. Within the hormonal health domain, CCTA provides a critical, structural assessment of the vascular tree, which is highly susceptible to the long-term effects of hormonal and metabolic dysregulation. It serves as a vital tool for advanced cardiovascular risk stratification.

Question 2

What is the Origin of CCTA?

Accepted Answer

This diagnostic modality evolved from conventional CT scanning and traditional catheter-based angiography, combining the high-resolution capabilities of CT with the vascular visualization afforded by contrast material. Its application in longevity medicine acknowledges the profound impact of endocrine aging, particularly the decline of protective sex hormones, on the progression of coronary artery disease. The technology allows for a structural snapshot of a key disease process influenced by the hormonal milieu.

Question 3

What is the Mechanism of CCTA?

Accepted Answer

The mechanism involves injecting an iodinated contrast agent into a peripheral vein, which transiently opacifies the coronary artery lumen, making the vessel visible on the rapid CT scan. The high-speed acquisition captures detailed, three-dimensional images of the beating heart. This process enables clinicians to accurately detect and characterize both calcified and soft, non-calcified plaque, providing a precise, non-invasive measure of cardiovascular health status influenced by systemic inflammation and hormonal factors.

CCTA

Meaning

Origin

Mechanism

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