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Causation Evidence

Meaning

Causation evidence represents the body of scientific data that rigorously demonstrates a direct cause-and-effect link between an antecedent factor, such as a specific hormonal imbalance or lifestyle choice, and a subsequent physiological outcome. This level of evidence transcends mere association or correlation, which only indicates two factors co-occur but does not explain their relationship. In clinical practice, establishing causation evidence is paramount for justifying therapeutic interventions and validating health claims. High-quality causation evidence is often derived from randomized controlled trials, offering the strongest basis for endocrine treatment guidelines.