What is the Origin of Catecholamine Mobilization?

This process is anatomically rooted in the Sympathoadrenal system, a subdivision of the autonomic nervous system, with the adrenal medulla being the primary endocrine source of epinephrine. The term 'mobilization' describes the rapid recruitment and release of these pre-synthesized neurotransmitters and hormones from storage vesicles. It reflects an ancient, evolutionarily conserved survival mechanism.

What is the Mechanism of Catecholamine Mobilization?

Upon activation by neural signals from the hypothalamus, the sympathetic preganglionic neurons stimulate the chromaffin cells of the adrenal medulla to release catecholamines. These hormones then bind to adrenergic receptors on target tissues, inducing a cascade of effects, including increased cardiac output, peripheral vasoconstriction, and glycogenolysis. This coordinated action rapidly mobilizes stored energy substrates to fuel the heightened metabolic demands of the musculoskeletal and nervous systems.

Catecholamine Mobilization ∞ Area

Catecholamine Mobilization

Meaning

Catecholamine Mobilization is the acute physiological event characterized by the rapid secretion of the stress hormones epinephrine (adrenaline) and norepinephrine (noradrenaline) into the systemic circulation. This process is a fundamental component of the body’s immediate, non-specific response to perceived threat, intense exercise, or significant psychological stress. The resulting hormonal surge prepares the body for immediate, high-demand action, which is often termed the “fight or flight” response.