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Catabolic Signal Dampening

Meaning

Catabolic Signal Dampening is a physiological strategy aimed at reducing the intensity and duration of biochemical signals that promote the breakdown of complex molecules, such as muscle protein and bone tissue, into simpler forms. This process is clinically relevant in managing age-related sarcopenia and metabolic stress, where excessive catabolism can lead to functional decline. The goal is to shift the cellular environment toward anabolism, thereby preserving lean body mass and structural integrity. Effective dampening helps maintain a more favorable anabolic-to-catabolic ratio, supporting long-term tissue health and resilience.