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Catabolic Drift Reversal

Meaning

Catabolic Drift Reversal represents the therapeutic objective of interrupting and reversing the progressive, age-associated shift in metabolic balance toward a net catabolic state, characterized by the breakdown of complex molecules and tissue loss. This physiological decline is a key driver of sarcopenia, bone demineralization, and general frailty. Successful reversal necessitates a strategic intervention to restore the body’s inherent anabolic capacity, favoring tissue synthesis and repair over degradation. Achieving this reversal is fundamental to maintaining functional independence and enhancing healthspan.