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Cardiovascular Risk after Oophorectomy

Meaning

Cardiovascular Risk after Oophorectomy refers to the increased probability of developing adverse cardiac and vascular events following the surgical removal of one or both ovaries. This procedure, particularly when performed premenopausally, results in an abrupt and significant decline in endogenous estrogen and androgen levels, fundamentally altering the hormonal milieu. The sudden loss of ovarian steroid hormones removes their protective effects on the endothelium and lipid profile, thereby accelerating the progression of cardiovascular risk factors. This clinical consideration necessitates careful patient counseling and proactive management of metabolic health post-surgery.