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Cardiovascular-Kidney-Metabolic Syndrome

Meaning

Cardiovascular-Kidney-Metabolic Syndrome, often abbreviated as CKM Syndrome, is a systemic, highly interconnected pathological state defined by the coexistence and mutual exacerbation of cardiovascular disease, chronic kidney disease, and metabolic disorders such as type 2 diabetes and obesity. This syndrome represents a unified clinical framework, emphasizing that dysfunction in one system significantly accelerates the deterioration of the others. Recognizing CKM Syndrome is essential for developing comprehensive, multi-organ treatment strategies in hormonal and metabolic health.