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Cardiorenal Protection

Meaning

Cardiorenal protection is a clinical objective focused on safeguarding the interdependent functions of the heart and the kidneys from progressive damage, particularly in the context of systemic diseases like hypertension, diabetes, and chronic kidney disease. This strategy recognizes the bidirectional relationship where dysfunction in one organ system inevitably exacerbates pathology in the other, leading to a cardiorenal syndrome. Therapeutic approaches aim to interrupt this vicious cycle by reducing volume overload, managing blood pressure, and minimizing neurohormonal activation. Optimal care requires integrated management to preserve the long-term viability of both cardiac and renal tissues.