What is the Origin of Cardiac Ejection Fraction?

The concept and measurement techniques for ejection fraction evolved with the advent of advanced cardiac imaging technologies, such as angiography and later echocardiography, in the mid-20th century. Clinicians needed a quantifiable, standardized metric to assess the mechanical performance of the heart independent of body size. It has become a standard, non-invasive metric in clinical cardiology to guide treatment decisions and monitor disease progression.

What is the Mechanism of Cardiac Ejection Fraction?

The ejection fraction is calculated by dividing the stroke volume—the amount of blood pumped out per beat—by the end-diastolic volume—the total amount of blood in the ventricle just before contraction. This ratio is then expressed as a percentage, reflecting the mechanical work efficiency of the myocardium. A reduced ejection fraction indicates impaired contractility, suggesting a failure in the heart's ability to respond adequately to the body's hemodynamic demands.

Cardiac Ejection Fraction ∞ Area

Cardiac Ejection Fraction

Meaning

Cardiac Ejection Fraction (EF) is a vital clinical measurement in cardiovascular physiology, representing the percentage of blood ejected from the left ventricle, the heart’s main pumping chamber, with each contraction. This metric serves as a key indicator of the heart’s systolic function and overall pumping efficiency, providing essential data for assessing cardiac health and diagnosing conditions like heart failure. Hormonal balance, particularly thyroid and growth hormone status, can significantly influence this crucial physiological parameter.