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Cancer Risk Promotion

Meaning

Cancer Risk Promotion refers to the phase in carcinogenesis where established pre-cancerous cells or abnormal tissue environments are stimulated to grow and proliferate, increasing the likelihood of developing a malignant tumor. This is distinct from initiation, which involves the initial genetic damage, and is often driven by chronic inflammation, sustained hormonal dysregulation, or exposure to specific non-genotoxic agents. In the hormonal health space, this concept highlights the critical need to manage endogenous and exogenous hormone levels to prevent unchecked cellular growth in hormone-sensitive tissues.