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Calcium Ion Flux Control

Meaning

Calcium Ion Flux Control refers to the highly regulated movement of calcium ions (Ca²⁺) across cellular membranes and into and out of intracellular stores, which is essential for signal transduction and numerous physiological functions. This precise control dictates the concentration of free calcium within the cytosol, acting as a ubiquitous and powerful second messenger. Proper regulation is vital for processes such as muscle contraction, neurotransmitter release, and the crucial secretion of many peptide hormones. Dysregulation in calcium flux is implicated in various pathological states.