Butyrate

Meaning

Butyrate is a short-chain fatty acid (SCFA) produced in the colon through the bacterial fermentation of dietary fiber, representing a critical metabolic link between the gut microbiome and host physiology. This molecule serves as the primary energy source for colonocytes, the cells lining the colon, promoting mucosal integrity and gut barrier function. Beyond the gastrointestinal tract, butyrate acts as a signaling molecule with systemic anti-inflammatory and epigenetic regulatory properties. Its presence is a strong indicator of a healthy, diverse gut flora, which is essential for overall hormonal and metabolic wellness.

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