Question 1

What is the Meaning of Brittle Nails?

Accepted Answer

Clinically referred to as onychoschizia or onychorrhexis, this condition is characterized by nails that are soft, easily broken, split, or peel in layers. It signifies a structural compromise in the nail plate's keratin matrix, often reflecting underlying systemic imbalances rather than just local trauma. The integrity of the nail unit is a visible indicator of overall physiological health.

Question 2

What is the Origin of Brittle Nails?

Accepted Answer

The term is descriptive, combining the Old English brytel, meaning easily broken, with nægl for the nail structure. In a clinical context, the physical presentation directs investigation toward internal regulatory systems. It is a common complaint in dermatology and endocrinology practices. The observation of nail changes has long been a part of clinical assessment.

Question 3

What is the Mechanism of Brittle Nails?

Accepted Answer

Hormonal fluctuations significantly impact the proliferation and differentiation of keratinocytes, the cells that form the nail plate. Hypothyroidism, for instance, slows metabolic rate and keratin production, resulting in thinner, weaker nails. Estrogen decline during perimenopause also reduces moisture content and collagen support in the nail bed, contributing to decreased flexibility and increased fragility. Optimal thyroid and sex steroid levels are essential for robust nail structure.

Brittle Nails

Meaning

Origin

Mechanism

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