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Brainstem Satiety

Meaning

Brainstem satiety refers to the immediate, fundamental signals originating in the brainstem that contribute to the termination of a meal and the feeling of fullness. This crucial physiological response is distinct from the longer-term satiety signals primarily regulated by the hypothalamus. It involves the integration of mechanical and chemosensory inputs from the gastrointestinal tract, providing rapid feedback on nutrient intake and stomach distension. This foundational regulatory mechanism is essential for controlling meal size and preventing acute overconsumption.