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Brain Receptor Sensitivity

Meaning

Brain Receptor Sensitivity refers to the degree of responsiveness of neuronal receptors to their specific neurotransmitter, neuropeptide, or hormonal ligands. This is a dynamic, highly regulated property of the central nervous system that determines the magnitude of a cellular response to a given chemical signal. Alterations in sensitivity, such as up-regulation or down-regulation, are fundamental mechanisms of neuroplasticity and adaptation to chronic stimuli. Clinically, maintaining optimal sensitivity is paramount for stable mood, balanced hormonal feedback loops, and efficient cognitive function.