Clinical and lifestyle strategies aimed at optimizing the brain’s intrinsic ability to reorganize itself by forming new neural connections throughout life. This support is vital for maintaining cognitive flexibility, enhancing learning capacity, and facilitating recovery from neurological insult. The endocrine system plays a substantial role in regulating the molecular pathways that underpin structural and functional neuroplasticity.
Origin
The term draws from the field of neurobiology, specifically the concept of neuroplasticity, which fundamentally changed the view of the adult brain as a static organ. “Support” places this biological principle within a practical, clinical context, focusing on modifiable factors like sleep, nutrition, and hormone optimization. It emphasizes proactive neuroprotection and longevity.
Mechanism
Support mechanisms involve regulating key neurotrophic factors, such as Brain-Derived Neurotrophic Factor (BDNF), which promotes the survival and differentiation of neurons and synapses. Hormones, including estrogen, testosterone, and growth hormone, directly influence the expression of these factors and the structural integrity of dendritic spines. Quality sleep is a primary physiological state for synaptic renormalization and consolidation of newly formed neural circuits.
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