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Brain Performance Ledger

Meaning

The Brain Performance Ledger is a conceptual framework utilized in clinical neuroendocrinology to track and assess the cumulative balance of neurobiological inputs and outputs that determine an individual’s cognitive reserve and functional capacity over time. It represents the net summation of beneficial factors, such as neurogenesis and hormonal support, versus detrimental factors, like oxidative stress and chronic inflammation. Clinicians use this concept to guide interventions aimed at maximizing neurological efficiency and mitigating age-related cognitive decline. Maintaining a positive ledger is crucial for sustained intellectual output and mental well-being.