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Brain Parenchyma

Meaning

Brain parenchyma refers to the functional tissue of the brain, comprising the two main classes of cells essential for neurological activity: neurons and glia. Neurons are the principal communication cells responsible for processing and transmitting information, while glial cells provide metabolic support, insulation, and maintenance of the microenvironment. This core tissue is distinct from the connective tissue, blood vessels, and cerebrospinal fluid spaces that support it. Maintaining the integrity and health of the parenchyma is directly correlated with cognitive function and neurological resilience throughout the lifespan.