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Brain Insulin Sensitivity

Meaning

Brain Insulin Sensitivity refers to the capacity of neurons and glial cells within the central nervous system to appropriately respond to the binding of insulin, a key metabolic hormone. Optimal sensitivity is vital for regulating energy homeostasis, modulating appetite, and supporting cognitive function, including memory and learning processes. Impaired brain insulin signaling, known as brain insulin resistance, is clinically implicated in neurodegenerative conditions and metabolic disorders. Maintaining this sensitivity is a crucial component of metabolic and cognitive health.