Brain Health Span refers to the period during an individual’s life where cognitive function, including executive processing, memory consolidation, and neuroplasticity, remains robust and unimpaired by pathology. It is the measure of high-quality neural longevity, distinct from total lifespan. Maintaining this span is central to sustained vitality.
Origin
This concept extends the established notion of “health span” into the specialized domain of neuroscience and cognitive longevity. It acknowledges that the functional capacity of the central nervous system is a critical determinant of overall well-being in aging. The term emphasizes function over mere structural presence.
Mechanism
Sustaining Brain Health Span requires optimal cerebral hemodynamics and efficient energy substrate delivery to neurons and glia. Hormonal support, particularly adequate levels of neurosteroids and thyroid hormones, plays a role in maintaining myelin integrity and synaptic receptor function. Furthermore, mitigating chronic neuroinflammation is essential for preserving the signaling fidelity across neural networks.
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