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Brain Fuel Substrate

Meaning

Brain Fuel Substrate refers to the primary metabolic compounds that the central nervous system utilizes to generate energy, essential for sustaining complex cognitive functions and neural integrity. Glucose is the brain’s main energy source, yet under certain physiological states, such as fasting or ketogenic diets, the brain efficiently switches to alternative compounds. These critical compounds power the synthesis of neurotransmitters, maintain ion gradients across neuronal membranes, and support overall neurological function. Adequate substrate availability is paramount for stable cognitive performance and mental clarity.