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Brain Bioavailability

Meaning

Brain Bioavailability quantifies the fraction of an administered compound—such as a nutrient, hormone, or pharmaceutical agent—that successfully traverses the blood-brain barrier and reaches its intended site of action within the central nervous system. This metric is critical for assessing the clinical efficacy of substances designed to influence neurological function, cognitive performance, or neuroendocrine regulation. A high brain bioavailability indicates efficient transport and minimal systemic metabolism before reaching the cerebral target tissue.