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Brain Aging Lipidomics

Meaning

Brain aging lipidomics is the comprehensive, quantitative study of the entire lipid profile—the lipidome—within the brain as it undergoes the physiological changes associated with chronological aging. This specialized branch of metabolomics seeks to identify specific lipid species, such as phospholipids, sphingolipids, and cholesterol esters, that change in concentration or structure over time. Clinically, shifts in the brain’s lipid signature serve as potential biomarkers for cognitive decline and neurodegenerative processes.