BPC-157 Systemic Healing refers to the therapeutic use of the synthetic peptide Body Protection Compound-157 to promote widespread regeneration and repair across multiple organ systems in the body. This approach is leveraged in clinical settings to accelerate recovery from musculoskeletal injuries, restore gastrointestinal integrity, and mitigate systemic inflammation. The term ‘Systemic Healing’ underscores the peptide’s pleiototropic effects throughout the human physiology.
Origin
BPC-157 is a stable gastric pentadecapeptide, meaning it is a short chain of fifteen amino acids derived from a protective protein naturally found in human gastric juice. Its origin in the stomach’s protective lining suggested its initial use for healing ulcers, but subsequent research revealed its potent regenerative properties across diverse tissues, establishing its role in broader systemic repair protocols.
Mechanism
The mechanism of action is multifaceted, primarily involving the stimulation of angiogenesis, which is the formation of new blood vessels crucial for delivering oxygen and nutrients to damaged sites. Furthermore, BPC-157 enhances the expression of growth hormone receptors in various tissues, promotes the migration and survival of fibroblasts for tendon and ligament repair, and modulates the nitric oxide pathway to improve blood flow and reduce local inflammation.
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