BPC-157 Neurological Effects refer to the observed influence of the synthetic peptide Body Protection Compound-157 on the central and peripheral nervous systems, particularly its capacity for neuroprotection and modulation of neurotransmitter systems. This peptide, a partial sequence of human gastric juice protein, exhibits systemic healing properties that extend into neurological tissues. Clinical interest centers on its potential to support recovery from neurological injury and mitigate neuroinflammation.
Origin
BPC-157 was originally synthesized and studied for its profound gastrointestinal protective and wound-healing capabilities, derived from a naturally occurring protein in the stomach. The discovery of its systemic and subsequently its neurological actions broadened its therapeutic scope, moving its clinical application into the domain of brain and nerve health. Its origin is firmly rooted in peptide chemistry and experimental pharmacology.
Mechanism
The neurological mechanism of action is multifaceted, involving the modulation of the dopamine, serotonin, and GABA systems, which are crucial for mood and cognition. Furthermore, BPC-157 has been shown to stabilize the blood-brain barrier and promote the survival of neurons by influencing growth factors like Vascular Endothelial Growth Factor (VEGF) and Nerve Growth Factor (NGF). These actions collectively support neurogenesis, synaptic repair, and the overall resilience of the nervous system against oxidative stress.
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