The therapeutic application of Body Protection Compound 157 (BPC-157), a synthetic pentadecapeptide, specifically to accelerate the healing and regeneration of damaged musculoskeletal tissues, including tendons, ligaments, and gut mucosa. This compound is utilized clinically to modulate local inflammatory responses and promote tissue remodeling. It represents a targeted strategy in regenerative medicine for acute and chronic injuries.
Origin
BPC-157 was initially isolated from human gastric juice, indicating an endogenous role in mucosal defense and repair mechanisms. Its scientific investigation began in gastroenterology before its application expanded into broader tissue repair contexts. The “157” denotes the specific sequence of 15 amino acids that constitute this active peptide.
Mechanism
The peptide primarily functions by upregulating growth hormone receptor expression and enhancing the local release of angiogenic factors, thereby increasing blood flow and cellular proliferation at the injury site. Furthermore, BPC-157 exhibits potent anti-inflammatory properties by influencing nitric oxide pathways. This dual action—promoting constructive healing while dampening excessive inflammation—is central to its observed efficacy in tissue repair kinetics.
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