Skip to main content

Bone Maturation

Meaning

Bone maturation is the complex, physiological process encompassing the growth, development, and eventual consolidation of the skeletal structure, transitioning from a cartilaginous model to fully ossified bone. This process is distinct from simple bone growth, as it involves structural changes, increases in bone density, and the closure of the epiphyseal growth plates. Hormonal signals, particularly growth hormone, insulin-like growth factor 1, and sex steroids, are indispensable regulators of this time-sensitive process. Clinical assessment of bone maturation, often via bone age radiographs, provides a crucial index of a child’s biological development and future growth potential.