What is the Origin of Body Fat Metabolism?

The term is a compound of "Body Fat," referring to adipose tissue, and "Metabolism," which comes from the Greek metabolē, meaning change or overthrow. This physiological concept has been studied since the early days of biochemistry and endocrinology, gaining renewed clinical importance with the recognition of adipose tissue's endocrine role.

What is the Mechanism of Body Fat Metabolism?

Lipogenesis, the synthesis of fat, is often stimulated by insulin, promoting the uptake of glucose and its conversion to triglycerides for storage. Conversely, lipolysis, the breakdown of stored fat, is stimulated by catecholamines and glucagon during energy deficits, releasing free fatty acids for use as fuel. Thyroid hormones and growth hormone also exert significant regulatory control over the rate of lipid turnover and thermogenesis within adipose tissue.

Body Fat Metabolism ∞ Area

Body Fat Metabolism

Meaning

The complex set of biochemical processes involving the synthesis, storage, and breakdown of lipids, primarily triglycerides, within adipose tissue and other organs. This metabolic process is crucial for energy homeostasis, providing a dense, readily available fuel source. Body fat is not merely an inert storage depot but an active endocrine organ, releasing adipokines and influencing systemic inflammation. Dysregulation of this metabolism is central to conditions like insulin resistance and obesity.