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BMP Signaling

Meaning

BMP Signaling refers to the intricate cell-to-cell communication cascade initiated by Bone Morphogenetic Proteins, which are a group of growth factors belonging to the transforming growth factor-beta (TGF-beta) superfamily. These signaling molecules are crucial for orchestrating cellular differentiation, proliferation, and apoptosis throughout the body, extending far beyond their initial identification in bone formation. In the endocrine system, they modulate the function and development of various glandular tissues.