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BMI-Adjusted Cut-Offs

Meaning

BMI-Adjusted Cut-Offs are specific diagnostic or reference thresholds for various biomarkers or clinical parameters that have been mathematically modified to account for an individual’s Body Mass Index (BMI). This crucial adjustment is necessary because body composition, particularly the volume of adipose tissue, significantly influences the synthesis, metabolism, and distribution of many hormones and metabolites. Utilizing these adjusted values improves diagnostic precision by reducing the misclassification of patients whose laboratory results are physiologically altered by their body habitus rather than by a primary endocrine disease state. They refine the interpretation of laboratory data for a more accurate clinical assessment of hormonal status.