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Biomechanical Signaling

Meaning

Biomechanical signaling refers to the complex process by which physical forces, such as mechanical tension or cellular stretch, are converted into biochemical signals within a cell. This sophisticated mechanotransduction process is essential for regulating gene expression, cellular behavior, and ultimately, systemic physiological adaptation in response to external stimuli. It represents a fundamental crosstalk mechanism between the body’s physical environment and its intricate molecular machinery, ensuring tissues like bone and muscle respond dynamically to loading.