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Biomarker Trajectory Modification

Meaning

Biomarker Trajectory Modification represents a targeted clinical approach aimed at intentionally altering the time-dependent progression of measurable biological indicators of health and aging. Instead of merely treating a current symptom or an isolated lab value, this strategy focuses on shifting the overall curve of a key biomarker—such as HbA1c, hs-CRP, or free testosterone—away from a predicted decline toward a more favorable, youthful range. This proactive modification is a core principle of preventative and longevity-focused medicine. The goal is sustained, long-term improvement in systemic function as evidenced by a changed slope in the biomarker’s trend over years.