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Biomarker Performance Ceiling

Meaning

The Biomarker Performance Ceiling is the theoretical or clinically observed upper limit of optimal functional capacity for a specific physiological or biochemical indicator. Beyond this point, further increase in the marker’s concentration does not yield proportional health benefits and may instead introduce detrimental or paradoxical effects. This ceiling defines the boundary of the therapeutic sweet spot for measurable health parameters, such as hormone levels, specific metabolic ratios, or inflammatory markers. Understanding this precise limit is crucial for personalized medicine, guiding clinicians to aim for optimal ranges rather than simply maximal values.