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Biomarker Guided Titration

Meaning

The clinical process of incrementally adjusting the dosage of a therapeutic agent, most commonly a hormone or peptide, based on serial, objective measurements of relevant physiological biomarkers. This precise method ensures that the final administered dose is optimally effective for the individual patient while remaining within a safe and physiologically appropriate range. It represents a cornerstone of personalized endocrinology, prioritizing quantitative data over generalized dosing protocols.