A structured set of interventions derived from translational science designed to enhance inherent biological capabilities beyond baseline homeostatic norms. These protocols are evidence-based strategies focusing on cellular resilience, mitochondrial function, and hormonal milieu optimization. We consider these deliberate steps toward improved physiological efficiency.
Origin
This term synthesizes “bios” (life) and “upgrading” technology concepts, applied to human biology as a framework for proactive healthspan extension. It implies a move from maintenance to active enhancement of physiological capacity.
Mechanism
The underlying mechanism involves leveraging hormesis, where controlled stressors or specific molecular inputs trigger adaptive responses. These responses often involve upregulating cellular defense mechanisms or improving receptor sensitivity within endocrine feedback loops.
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