What is the Origin of Biological Time Horizon?

The term draws from the intersection of chronobiology, gerontology, and risk assessment modeling, moving the abstract concept of lifespan into a quantifiable, clinical framework. 'Biological' emphasizes the focus on intrinsic physiological markers, while 'Time Horizon' reflects a forward-looking, predictive clinical utility for healthspan planning.

What is the Mechanism of Biological Time Horizon?

Determination of the Biological Time Horizon involves measuring and integrating various biomarkers of aging, such as telomere length, epigenetic clocks, inflammatory markers, and hormonal profiles. These data points are synthesized to calculate a biological age, which is then extrapolated against population data to estimate the remaining healthspan. By modulating the underlying physiological drivers of aging, clinical interventions aim to extend this functional time horizon.

Biological Time Horizon

Meaning

A clinical concept representing the projected duration of an individual’s healthy, functional life based on their current biological age and rate of physiological decline. This metric transcends chronological age by integrating multiple biomarkers of cellular and systemic health, offering a more dynamic assessment of longevity potential. The horizon is not fixed but is actively influenced by lifestyle, environment, and therapeutic interventions.