Biological System Engineering is the application of engineering principles to model, analyze, and purposefully redesign complex physiological networks, including endocrine signaling pathways. We seek to understand the system as an integrated whole rather than isolated components.
Origin
This discipline emerges from systems biology, incorporating computational modeling and feedback control theory into the study of living organisms. It represents a paradigm shift toward proactive physiological design.
Mechanism
The mechanism involves creating dynamic models of hormone kinetics and receptor interactions to predict how specific perturbations will affect system stability. Engineering interventions are then designed to enforce desired set points, much like calibrating a control system.
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