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Biological Set Point Alteration

Meaning

Biological Set Point Alteration describes the therapeutic objective of modifying the homeostatic baseline around which a specific physiological parameter is regulated by the body. In the context of hormonal health, this refers to deliberately shifting the target range for metrics like body fat percentage, core body temperature, or the optimal concentration of a circulating hormone, such as testosterone or thyroid hormones. This alteration moves the system away from a suboptimal, often age-related, baseline toward a more youthful and functionally robust equilibrium. Achieving this change requires sustained intervention to reset the hypothalamic-pituitary-adrenal (HPA) or hypothalamic-pituitary-gonadal (HPG) axis feedback loops.